Copy a blank template (system_file="template") file to the working directory or an example by specifying the following:

  • "template" - Empty system file template

  • "adapt" - Parent/metabolite model taken from the adapt manual used in estimation examples [ADAPT]

  • "two_cmt_cl" - Two compartment model parameterized in terms of clearances

  • "one_cmt_cl" - One compartment model parameterized in terms of clearances

  • "two_cmt_micro" - Two compartment model parameterized in terms of rates (micro constants)

  • "one_cmt_micro" - One compartment model parameterized in terms of rates (micro constants)

  • "mab_pk" - General compartmental model of mAb PK from Davda 2014 [DG]

  • "pbpk" - PBPK model of mAb disposition in mice from Shah 2012 [SB]

  • "pbpk_template" - System parameters from Shah 2012 [SB] have been defined for all species along with the set notation to be used as a template for developing models with physiological parameters

  • "pwc" - Example showing how to make if/then or piece-wise continuous variables

  • "tmdd" - Model of antibody with target-mediated drug disposition

  • "tumor" - Transit tumor growth model taken from Lobo 2002 [LB]

system_new(
  file_name = "system.txt",
  system_file = "template",
  overwrite = FALSE,
  output_directory = getwd()
)

Arguments

file_name

name of the new file to create

system_file

name of the system file to copy

overwrite

if TRUE the new system file will overwrite any existing files present

output_directory

getwd() directory where system file will be placed

Value

TRUE if the new file was created and FALSE otherwise

Details

References

Examples

# \donttest{
# To create an example system file named example_system.txt:
system_new(system_file      = "mab_pk", 
           file_name        = "system_example.txt", 
           overwrite        = TRUE,  
           output_directory = tempdir())
#> [1] TRUE
# }